Have legs will travel

Have tRNA, will travel.

T he processing of tRNA is deceptively complicated from the standpoint of both biochemistry and spatial organization. Every generation in yeast, 3–6 million tRNAs are processed (1), 10 times the number of rRNAs and 60–100 times the number of mRNAs (2). Processing of tRNAs requires 60 polypeptides to catalyze removal of the 5 leader sequence, trimming of the 3 trailer sequence, splicing of the i...

Have virus, will travel.

prevent introductions from region to region. Meanwhile, the international community has failed to prevent a stream of species from flowing around the world, with the exception of a 1951 agreement to prevent introductions of plant pests. President Clinton's executive order creates a federal interagency Invasive Species Council whose members include the secretaries of state, treasury, defense, th...

Agrobacterium-plant cell DNA transport: have virulence proteins, will travel.

Agrobacterium fumefaciens (Agrobacterium) is a soil phytopathogen that genetically transforms host cells, causing crown gall tumors, an agronomically important disease that affects most dicotyledonous plants. In nature, these tumors are formed at the soil-air junction, the so-called crown of the plant. The Agrobacterium-plant cell interaction is the only known natural example of DNA transport b...

Make junction, will travel

ny cell therapy risks introducing mutated and possibly tumorigenic cells. Now results from Peter Stambrook (University of Cincinnati, Cincinnati, OH) and colleagues underline this concern for embryonic stem (ES) cells, which are one possible source for therapeutic cells. Stambrook constructed a cell line in which he could detect loss or mutation of a heterozygous marker gene. Loss (rather than ...

Have Framework, Will Travel: Extending the Frameworks into Transnational Higher Education